NONSTERIODAL ANTI-INFLAMMATORIES - a patient's guide
Abstract
NSAIDs are commonly used to treat painful inflammatory conditions such as arthritis. This article profiles the medicines and their side effects.
TYPE/ BRAND:
- Aspirin - Solprin
- Diclofenac - Voltaren
- Ibuprofen - Brufen
- Indomethacin - Indocid
- Ketoprofen - Oruvail
- Naproxen - Naprosyn, Synflex
- Tenoxicam - Tilcoltil
- Tiaprofenic - Surgam
USE: Anti-inflammatory
Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin synthesis which is regarded as an important part of the pain and inflammatory process. They have a combined analgesic (pain relief) and anti-inflammatory effect which is particularly useful for the treatment of rheumatoid arthritis, osteoarthritis, gout, migraine, surgery trauma, dental pain, and soft-tissue injuries.
Caution:
- Previous allergy to NSAIDs
- Stomach ulcer history
- Kidney impairment
- Pregnancy (avoid in 3rd trimester)
- Asthmatics
- Increased risk of side effects in elderly (especially women)
- Breastfeeding
Side effects:
Occasional: stomach upset, headache, dizziness.
Rarely: skin rash, gastric-bleeding, oedema, bronchospasm/worsening of asthma symptoms (5-10% of asthmatics).
Interactions:
Caution must be exercised with B-blockers, thiazide and loop diuretics, lithium, digoxin, warfarin, quinolone antibiotics and immunosuppressants.
Patient information:
- Follow instructions on the label of this medicine.
- Do not exceed the maximum dosage as directed by your doctor.
- Food: Taken after food with a large glass of water
- Alcohol: May prolong inflammation and swelling and increase risk of stomach bleeding
- Avoid taking other NSAID over-the counter preparations (Nurofen, Cataflam, Disprin etc).
- Contact your doctor or seek medical help if side effects are severe or ongoing.
- Discuss any symptoms of abdominal pain, nausea, vomiting with your doctor - the medication may need to be stopped.
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